In this case we did about 1/3 of the lake to reduce trash fish. This was a river effected (about every 3rd year) oxbow type lake. Done in conjunction with Wildlife and Fisheries as they also wanted to see the results also. After everyone was finished I decided to fish.
Have also seen rotenone used on spawning beds to limit reproduction. Guarding fish swim off and rotenone mixture is poured around encircling the nest site.