I believe wolves were what originally held coyotes out of most of North America, leaving them in the hot/arid areas where we are used to seeing them chase Road Runners (smaller bodies = easier heat dissipation ???). Removal of wolves, which cannot live in close proximity to man, has left a huge expanse of territory open to Wile E.'s friends & relatives, who have no trouble making a living in the 'burbs and more open cities (i.e. JHAP's SoCal).