Lancaster County, VA in North Eastern part of the state, no elevavation, near the Chesapeake Bay.
Your location actually has a higher average annual temperature than the Oklahoma lake in ewest's musky study. However, I suspect the Oklahoma lake has colder winters and warmer summers. It is the summer heat that most stresses the muskies, so you might be a tad less than the study lake.
I think musky might "live" in your lake, but it would be tough for them to "thrive". (Total non-expert, non-local opinion!)