To the original question, I think knowing the individual bullet and how it will react is more important, after the gun is chose.
I carry a .357 and had it loaded with home defense loads. Had the opportunity to Finish an elk as such happens when elk hunting with friends. 3 rounds never broke the skin at point blank.
Used .38 specials and they worked great on a different friends hunt.
I once owned a Raging Bull Casual also!! that gun was awesome and very accurate. I carried it for bear spray in MT but in SD now and dont have many of those.
Any fans of the .460?? that is a cool round.
