Good question on the HCG, Cecil. I didn't know, and you made me curious. I checked online and if we can trust what I found....

Like other gonadotropins, hCG can be extracted from urine or by genetic modification. Pregnyl, Follutein, Profasi, and Novarel use the former method, derived from the urine of pregnant women. Ovidrel, on the other hand, is a product of recombinant DNA.
Even back to the earliest days of me being in the fisheries profession, we were using HCG. My first exposure came in ND, where they used it to ripen the green female walleyes for spawning. That was back in the mid-70s.