The 243, 22-250, and 25-06, are all great rounds IMO. The 243 has a good punch but a little slower, the 25-06 will reach out there farther but kicks harder as well. The 22-250 has great velocity but with something as big as a hog shot placement will be important. Keep in mind too that all of these guns esp 243 and 25-06 can have a muzzle break installed on the end relatively cheap and that will reduce the recoil of the 25-06 to that of a 22-250 maybe a little less. To me accuracy is key if you cant shoot the 25-06 without flintching whats the punch power got over the 22-250? Something to consider.
