I can't stand organic chemistry. It drives me crazy. Biochem on the other hand, I love it.
If I can relate what I am doing to an organism and a physiological process, then I am golden.
The O-Chem is just a bunch of chemicals in a jar to me. I have lightbulb moments every once in awhile about how it can be useful. For example, it finally made sense to me how to make "crack" cocaine from pure cocaine. I guess thats not all that useful unless I went on to become a drug lord.